Summary

Phenylpiracetam is one of the most potent nootropics that are available on the market today. Phenylpiracetam was created at the Russian Academy of Sciences in 1983 as a medication to help support their cosmonauts during their space missions.

It is a racetam class nootropic and is a modified version of the original nootropic piracetam, except it is estimated to be 30 to 60 times more potent, has improved neuroprotective properties, and enhances physical performance. For these reasons, phenylpiracetam is rapidly gaining recognition among nootropic enthusiasts.

Structurally, phenylpiracetam is essentially piracetam with a phenyl group attached to it. The addition of the phenyl group improves upon piracetam in the following two ways:

  1. Increased Potency – The addition of the phenyl group improves its ability to pass the brain-blood barrier (BBB) making it more bioavailable where it’s needed most.
  2. Energizing – More stimulating effects due to a closer resemblance to a phenethylamine substance, such as Adderall.

In comparison to other racetams, phenylpiracetam is quite potent and has a high bioavailability (~100%) even when ingested orally.[1]

Benefits and Effects

Phenylpiracetam increases memory and overall cognition more effectively than piracetam, protects the brain, and has been reported to enhance physical performance.

Phenylpiracetam is a great addition to nootropic stacks due to its powerful fast-acting effects. Specifically, athletes and students may benefit the most due to its stimulating and motivating properties. It also provides an increased tolerance to stress which may be attractive for individuals with demanding lifestyles.

Phenylpiracetam has been given to Russian cosmonauts, notably Aleksandr Serebrov on his 197-day voyage, for its ability to enhance the performance of both the mind and body under high stress. Serebov described phenylpiracetam’s as an “equalizer of the whole organism” and “completely excluding impulsiveness and irritability, inevitable in the conditions of high nervous tension of space flight.[2]

Phenylpiracetam has demonstrated the following effects in scientific studies:

  • Improve memory, attention-switching, and problem-solving skills in patients with asthenia.[3]
  • Increase locomotor and antidepressant activity and improve memory in animal studies.[4]
  • Shown to prevent and reduce the effects of amnesia in animal studies.[5]
  • Ability to suppress the anxiety and fear response in rats with induced immune stress.[6]
  • Reduces the effects of cold on our body by increasing one’s tolerance to it.[7]

Studying and Learning

The benefits of phenylpiracetam may be especially useful for studying and learning. Its stimulating nature is great for an otherwise sleep-deprived study session, pretest focus aid, or just a general cognitive enhancer. Its positive effects on memory allow may allow for improved retention.

It’s mood enhancement properties may indirectly improve mental performance as well.

Finally, its ability to reduce the effects of stress and anxiety should allow for optimal mental performance even while under pressure.

Athletes

Phenylpiracetam is also great for working out and enhancing athletic performance. It mitigates the harmful effects of stress on the body, which is invaluable for an athlete, while increasing stamina, recovery, and endurance.

Phenylpiracetam provides an energizing effect similar to that of an amphetamine. A clean, focused, motivated energy without the caffeine jitters may help optimize performance during workouts or competitions. There also is little to no crash, even compared to caffeine.

Professional athletes should note that phenylpiracetam is on the World Anti-Doping’s prohibited in-competition list and should decide on whether to supplement with it accordingly.[8]

How it Works

While the benefits of supplementing phenylpiracetam have been demonstrated inside and outside the lab, its exact mechanism of action is not fully understood.

Phenylpiracetam’s energy boosting properties likely exist due to its close resemblance to phenylethylamine, an organic compound which is known for its stimulatory effects. The benzene ring of the phenyl group likely also increases the affinity for neurotransmitter (norepinephrine and dopamine) transporters.

Dosage

A typical dose of phenylpiracetam ranges from 100-250 mg per dose, taken with meals, up to three times a day.[9] Due to its potent effects, it is recommended to start at the lower end of the dosage range and then to increase if necessary.

Tolerance to phenylpiracetam’s acute energizing effects are reported to develop relatively quickly. Therefore, if interested in preserving its energizing effects, it is not advised to take it as a daily supplement but to instead restrict use to when it’s needed most or to cycle it periodically.

Stacking

Here is an example of how phenylpiracetam can be combined with other nootropics, for enhanced effects.

Daily

As Needed for Studying/Workouts/Tests

This stack is especially suitable for students or athletes. A healthy balanced daily routine while saving the powerful effects of phenylpiracetam for when it is needed most, enhancing just about every aspect of your mind and body.

Expect enhanced motivation, focus, energy, a reduced need for sleep, increased stamina, and improved mood.

Phenylpiracetam is an excellent example of the potential of nootropics.

Side Effects

Like other nootropics in the racetam class, there are few reported side effects from supplementing phenylpiracetam when taken at the recommended dosages.

If you do experience headaches, it may be a sign that you should add or increase your choline supplementation, which is usually recommended when taking racetams.[10][11]

Where to Buy

Phenylpiracetam can be ordered online from PureNootropics.net. They are one of our favorite suppliers for our nootropics, their packaging is fantastic, and their batches are tested for purity by third-party labs.

Always stick to reputable vendors when buying nootropics.

Closing Thoughts

Phenylpiracetam is quickly gaining popularity with nootropic users for its powerful effects. Consider trying it out as an exciting alternative to the more common racetams.

As always, it is recommended to start out by taking a low dosage, without other nootropics, to gauge your sensitivity to it.

References   [ + ]

Planning to start a new supplementation regimen? See our medical disclaimer.