Mind Lab Pro Review

Today, I am going to review Mind Lab Pro. This pre-made nootropic stack was designed by Opti-Nutra. I had been hearing more and more buzz about it on forums and reddit.com over the last year, so I wanted to check it out for myself.

Now that I have been using it for the last two months, here is my report.

Pre-made nootropic stacks such as Onnit Lab’s Alpha Brain, and Maven Labs’ BrainStack are growing in popularity, in pace with the booming market in brain supplements and cognitive enhancers.

So how does Mind Lab Pro compare to these other stacks that I have reviewed over the last couple of years?

Mind Lab Pro falls into the category called “nutraceuticals” like Alpha Brain, BrainStack and CILTEP. The ingredients are all natural.

Each company has their own philosophy on stack ingredients, quantities, and their approach to brain optimization. But Opti-Nutra has a unique take on how to go about enhancing the brain.

Onnit promotes Alpha Brain as a nootropic stack to help you with memory, focus, and processing speed. Maven Labs emphasizes focus and productivity. Natural Stacks’ CILTEP was designed primarily to boost long-term memory.

Mind Lab Pro, on the other hand, is promoted as the first “Universal Nootropic.” While other stacks target 2 or 3 brain pathways, Opti-Nutra designed this stack to unlock every area of your brain.

Mind Lab Pro’s strategy aims at all aspects of memory, mental performance, mood and stress resistance, maintenance, and brain repair. Their combination of nootropics is designed to affect brain energy, neurotransmitters, brain blood flow, brain waves, neuroprotection, and regeneration.

Sounds like a tall order for a nootropic stack. So let me start by saying that my experience with Mind Lab Pro has been exceptional. Here’s my review.

Mind Lab Pro Ingredients

The ingredients for Mind Lab Pro are a step above any other pre-made nootropic stack I have reviewed. Some of the ingredients are similar to Onnit’s Alpha Brain and Maven Labs’ BrainStack. With some significant differences.

The quantities for Mind Lab Pro are spelled out in detail on the label like BrainStack. Alpha Brain, on the other hand, uses an undisclosed “proprietary formula” for most of their stack. You don’t know exactly how much of each ingredient they are using.

Another main difference is Mind Lab Pro’s use of vinpocetine as the primary neurovasodilator. Unlike both Alpha Brain and BrainStack who use Huperzine A.

Now, I am not saying Huperzine A is not a great way to get cerebral blood flow going. It is. But Huperzine A has at least a 24-hour half-life. So most prefer cycling this nootropic as opposed to dosing it daily. This means using Huperzine A every 2nd day, or even only twice per week. That is impossible to do when it is already blended into your preformulated stack that you want to take daily.

The other main difference is in the quality of ingredients in Mind Lab Pro. Wherever possible the company uses premium patented compounds containing verified ingredients and potency. For example, Cognizin instead of plain citicoline. Or Suntheanine instead of regular L-Theanine. It’s more expensive this way but at least you know you are getting the very best available ingredients.

Here is the list of ingredients in Mind Lab Pro:

  • 175 mg N-Acetyl-L-Tyrosine
  • 100 mg L-Theanine (Suntheanine®)
  • 100 mg Phosphatidylserine (Sharp PS® Green)
  • 250 mg Citicoline (Cognizin®)
  • 150 mg Bacopa Monnieri (45% bacosides)
  • 6 mg Vinpocetine
  • 500 mcg Pterostilbene
  • 500 mg Lion’s Mane
  • 50 mg Rhodiola Rosea (3% rosavins & 1% salidroside)
  • 2.5 mg Vitamin B6 (P-5-P)
  • 7.5 mcg Vitamin B12 (methylcobalamin)

These amounts are based on a typical dose of 2 capsules. If you take the maximum daily dose of 4 capsules, the amounts above double, which makes for a potent stack. For most people, myself included, 2 capsules per day is sufficient.

You can have a look at the official Mind Lab Pro Ingredients Page for even more information.

Mind Lab Pro Ingredient Review

Opti-Nutra has taken a unique approach in designing the Mind Lab Pro stack. Each nootropic used in this stack provides multiple brain-boosting activities. There are no single-taskers included. Which means you can use fewer individual nootropics to achieve the same brain optimization goals. When combined, smaller amounts of each can be used to get the same effect.

Citicoline (Cognizin®)

Citicoline is used by most neurohackers to boost acetylcholine in the brain. Especially important when you are using anything from the racetam-family. But citicoline does so much more for brain optimization.

This multi-tasking nootropic, citicoline affects each of the 6 brain pathways; brain energy, neurotransmitters, brain blood flow, brain waves, neuroprotection, and regeneration.

Once digested, citicoline is converted into cytidine and choline. The choline is used to synthesize acetylcholine and increase levels of dopamine which assists in attention, cognition, concentration, focus, mood, learning and memory.

Cytidine can convert into uridine which is needed to synthesize phosphatidylcholine (PC) for brain cell membranes. It helps repair neurons. Citicoline increases brain energy and speeds up the formation of brain cell membranes. It increases blood flow to the brain. Citicoline also boosts brain signal transmission.


Tyrosine is an amino acid use to synthesize the catecholamines dopamine, epinephrine, and norepinephrine. Tyrosine also helps restore neurotransmitters that are depleted by stress. So we cover neurotransmitters and regeneration with this nootropic. Opti-Nutra uses N-Acetyl-L-Tyrosine because it is more bioavailable than regular tyrosine.

The acetyl group also serves as a substrate for acetylcholine synthesis when taken in combination with citicoline.

L-Theanine (Suntheanine®)

L-Theanine, which occurs naturally in green and oolong tea, is an amino acid. This multi-tasking nootropic addresses brain waves, neuroprotection, and neurotransmitters.

Studies show L-Theanine helps boost alpha and theta brain waves which are associated with relaxation, creativity, and relief from trauma. It increases GABA, serotonin and dopamine levels in the brain. As well as boosting Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF). Providing an energizing and calming effect while improving cognition and memory. L-Theanine is also an antagonist of NMDA receptors which inhibits the release of glutamate, protecting your brain from over-stimulation.

Phosphatidylserine (Sharp PS® Green)

Phosphatidylserine (PS) multitasks by boosting brain energy, neurotransmitters, provides regeneration and affects brain waves. PS makes up about 15% of the total phospholipid pool in your brain.

As part of the inner cell membrane, PS helps maintain brain cell membrane fluidity, optimizes neuroreceptors, and helps boost acetylcholine and dopamine. It helps brain cell energy by enhancing glucose metabolism. PS increases Nerve Growth Factor (NGF) which helps neurogenesis, maintenance, and repair. PS also helps immune cells take out the cellular garbage which spares neighboring cells from damage.

Mind Lab Pro uses Sharp PS® Green which is derived from sunflower lecithin. Helping you avoid soy.

PS also serves as a phosphatidyl donor for phosphatidylcholine synthesis, when taken in combination with citicoline.

Bacopa Monnieri

Bacopa helps boost neurotransmitters, brain energy, cerebral circulation and offers neuroprotection. The ancient Hindus liked it so much they named it “Brahmi,” after their supreme god Brahma.

Bacopa is considered an adaptogen. The active compounds bacosides A and B improve electrical signaling between neurons, and help rebuild damaged neurons. It promotes the enzymes needed to protect neurons from free radical damage. Bacosides assist acetylcholine, GABA, and serotonin which lead to focused thinking, clear memory and better mood. Research shows it may even boost cerebral blood flow.


Vinpocetine is synthesized from the periwinkle plant. As a nootropic, Vinpocetine is best known for enhancing cerebral circulation by inhibiting the PDE1 enzyme. More blood flow promotes glucose and oxygen utilization to feed brain cells. Improving alertness, cognition, concentration, memory and mood.

But Vinpocetine provides more than just better blood flow. It blocks sodium in neurons, reduces the toxic effects of stress, scavenges free radicals and protects neurons from glutamate and NMDA toxicity.

When enzyme PDE1 is inhibited, cAMP and cGMP are increased, which in turn activates a series of kinases that phosphorylate transcription factors which boosts neuroplasticity, enhancing cognition and memory.


Pterostilbene is a highly bioavailable polyphenol found in grapes and blueberries. As part of the Mind Lab Pro formula, this nootropic helps neurotransmitters and offers neuroprotection.

Pterostilbene increases hippocampus neurogenesis, boosts insulin-like growth factor-1 (IGF-1), and modulates the receptor kinase pathway that is central to learning and memory. It has also been shown to prevent the loss of dopamine from memory centers in your brain.

This polyphenol is a potent antioxidant and anti-inflammatory. It reduces reactive oxygen species and increases the antioxidant superoxide dismutase (SOD). Pterostilbene has been shown in clinical trials to elevate Brain-Derived Neurotrophic Factor (BDNF) in the hippocampus. Improving learning and memory.

Lion’s Mane Mushroom

Lion’s Mane is the only known mushroom that supports brain health. It’s in Mind Lab Pro to provide neuroprotection and brain cell regeneration.

Lion’s Mane is known for preventing and treating nerve damage in the brain. It stimulates enzyme production that releases Nerve Growth Factor (NGF). NGF are proteins that function to regenerate neurons, modulate cholinergic receptors and provide the neuroplasticity essential for learning.

In practice, Lion’s Mane has been shown to be effective in reducing anxiety and depression. It works to improve cognition, memory and works as an antidepressant.

Rhodiola Rosea

Rhodiola as a nootropic affects brain energy, neurotransmitters and offers brain cell regeneration. It helps reduce stress and fatigue, increases alertness and stamina, while boosting mental performance under periods of chronic stress.

Rhodiola influences serotonin and norepinephrine levels in the brain, and the feel-good opioids beta-endorphins. It also helps in neurogenesis by repairing and growing new neurons. It activates the synthesis and re-synthesis of ATP, your brain cell’s main energy source. Salidroside, one of many components in Rhodiola protect neurons from oxidative stress-induced cell death.

Vitamin B6 (P-5-P)

Vitamin B6 as a nootropic affects brain energy, neurotransmitters, cerebral blood flow and offers neuroprotection. It helps your brain make serotonin, norepinephrine, and melatonin. It helps control homocysteine, and along with Vitamin B12, helps make red blood cells and immune system cells.

Vitamin B12

Vitamin B12 is in Mind Lab Pro to assist brain energy and neurotransmitters. Vitamin B12 plays a role in the efficient conversion of carbohydrates to glucose which is your cell’s source of fuel. It also helps convert fatty acids into energy.

Vitamin B12 is required for the synthesis of DNA, RNA and neurotransmitters, the maintenance of myelin sheaths protecting axons, and red blood cell formation. It’s a cofactor in the synthesis of dopamine, GABA, norepinephrine, and serotonin.

Both B6 and B12 are needed to ensure this nootropic stack works efficiently.

Ingredient Synergy

The first thing you notice when looking at the label of Mind Lab Pro is that it shows exactly how much of each ingredient is in each dose. The next thing you notice is that the amount of each ingredient is fairly modest (based on 2 capsule dose – at 4 capsules, the ingredients are at a high-potency).

Now after looking at how each nootropic in this stack affects several different pathways in the brain, each from a different angle. The combination is a brilliant approach to maximizing the effect of the entire stack. Each ingredient works in synergy with the rest of the stack.

This all-natural formula is amazingly effective in promoting brain energy, cognition, memory, and mood.

Mind Lab Pro Review of Effects

Opti-Nutra promotes Mind Lab Pro for “100% Brainpower.”

Having tried many different nootropic stacks over the years, the first thing I noticed with MLP was that I started feeling the effects soon after taking my first two capsules.

It wasn’t so much an overwhelming sense of something happening in my brain. It’s just that I had a huge improvement in mental clarity right away.

Increased Focus

With Mind Lab Pro, focusing seems effortless. It seems easier to concentrate and stay focused on the task at hand for hours on end. With no mental fatigue.

My response time both at work, in traffic, and even playing basketball is faster. I feel sharper and more alert. Calculation and judgment are much better. Mind Lab Pro gives me an edge that I haven’t experienced in a long time.

Improved Memory

My memory improved when using Onnit’s Alpha Brain. With Maven Labs’ BrainStack it got even better. Then with Mind Lab Pro, memory went to a whole new level.

MLP seems to affect all aspects of memory. Short-term, long-term and working memory. Decision-making is faster. I no longer have to make lists days in advance of tasks for the week ahead. Words seem to come easier. My vocabulary seems to flow. Words and songs come up that I haven’t thought of in a long time.

Improved memory has been a huge help in helping me to communicate better. Both with my customers and even family and friends. I just remember things much easier in daily life.

Better Mood

Since starting on Mind Lab Pro, I have found that my anxiety levels are greatly reduced. Part of it is likely because focus, memory, and motivation are all better. But the edges have been tamed. Not dumbed down. Just the anxiety knob has been turned down to zero.

Mental fatigue is greatly reduced. So instead of feeling tired midway through my day, things are still going strong. I do not normally have depressive tendencies for which I’m grateful. But with MLP, my quality of life simply feels better.

I would recommend Mind Lab Pro to anyone who feels they want an edge. This truly is “One Nootropic Formula For All.”

Anyone would benefit from using Mind Lab Pro. Students, athletes, anyone in competitive sports or gaming, professionals and those of you over 55.

Here’s what I liked…

  • Better short- and long-term and working memory
  • Alertness, concentration, focus and motivation
  • Response times are better
  • Decision-making is faster and better
  • 2 capsules last the entire day
  • Dramatically reduced anxiety levels
  • Better mood and quality of life
  • Top-tier ingredients
  • Quality assurance tested before, during and after encapsulation
  • 100% natural plant-based capsules instead of semi-synthetic veggie “cellulose” capsules or standard gelatin capsules
  • Exceptionally high-quality product, outstanding value for money
  • Fast worldwide shipping, great guarantee, easy payment

Have a look the Mind Lab Pro “How It Works” page to learn more about the methodology used when they formulated their blend.

The Verdict

Would I recommend Mind Lab Pro? If I could give it a 6 out of 5, I would.

Mind Lab Pro is the best pre-made all-natural nootropic stack I have tried so far. It is the best all-natural supplement stack for total brain optimization.

I absolutely give it a 5 out of 5 rating.

Opti-Nutra claims that Mind Lab Pro is the cleanest brain supplement ever developed. No additives. No fillers. Just pure “100% Brainpower.”

All the ingredients are tested prior to encapsulation to make sure they are free of allergens, GMO’s, microbes, pesticides, and herbicides. The plant-based capsules are made out of tapioca, a prebiotic fiber. Not a semi-synthetic polymer used by others in this market. Finished batches are re-tested to confirm potency, purity, and activity. All their packaging is recycled or biodegradable.

Mind Lab Pro is an excellent choice for a premium natural preformulated stack. You are paying for a quality product that is composed of the very best ingredients.

Whether you are looking for an easy “ready to go” introduction to nootropics, or you are an advanced nootropic user looking for a convenient foundation to build upon (such as stacking it with aniracetam or Noopept), Mind Lab Pro is a solid choice.

This is now my favorite pre-made nootropic stack. I use it regularly to give me the edge I need.

Visit MindLabPro.com to get Mind Lab Pro and experience its brain optimizing effects for yourself.

Planning to start a new supplementation regimen? See our medical disclaimer.